徐 立
副教授，碩士生導師
簡歷
1996 - 2000 西南農業大學，蠶絲生物科學🤹🏻♂️，學士；
2000 - 2003 西南農業大學，特種經濟動物飼養，碩士；
2000 - 2003 西南大學，特種經濟動物飼養👭🏼，博士😌；
2004 - 2006 中科院昆明植物所植物化學國家重點實驗室😆，客座博士研究生👨🏻🦽➡️；
2006 - 至今 西南大學👩🏻🦲，教師🏄♂️；
2015 - 2016新加坡國立大學食品系🪱，訪問學者🫅🏼。
課程教學：
本科生課程𓀓：
《生化分離與分析技術》🥈、《植物功能物質開發利用》🍍、《Natural Medicinal Chemistry》💠🙂↕️、《Natural products Chemistry》、《Biochemical Separation and Analysis Techniques》
研究生課程：
《生物醫藥產業進展》
主要研究領域
1. 植物次生代謝產物的分離鑒定、活性（抗衰老、美白、抗炎👮🏻♀️、降血糖、抗病毒、抗菌、抑製阿爾茲海默症等）評價、作用機製研究及相關產品開發；
2. 植物細胞培養（生物合成護膚品及藥品領域急需重要次生代謝產物）✊🏽。
主要科研成果
主持和參研40余項科研課題🧎➡️；
以第一發明人申請國家發明專利19項（授權12項，轉化2項）🤸🏻；
在國內外學術刊物發表論文90余篇（第一作者或通訊作者70余篇）。
所獲榮譽
2022年獲“2020-2022學年度優秀教師”🏋🏿🌚；
2018年獲“2016-2018學年度優秀教師”；
2016年獲“重慶市第七屆“科慧杯”研究生創新創業大賽優秀指導教師”；
2012年獲“第二屆西南大學教學成果一等獎”（4/5）🤱🏽；
2011年獲“2010―2011年度農業部“中華農業科技獎”二等獎”（12/15）；
2011年獲“西南大學第六屆教師課堂教學比賽”優秀獎🧎♂️➡️🎬；
2007年獲“教育部科技進步獎（推廣類）二等獎”（11/12）
指導學生參加“創業大賽”🏌🏽、“挑戰杯”、“互聯網+”比賽，獲得“國家銀獎”、“國家銅獎”♾、“國家三等獎”、“重慶市金獎”🍅、“重慶市特等獎”等獎項。
社會/學術兼職
全國萬名優秀創新創業導師；
國家、重慶市“三區”科技特派員；
Industrial Crops and Products, Journal of agriculture and food chemistry, RSC Advances, Pharmaceutical Biology, Biomedicine & Pharmacotherapy, Food & Function, Phytomedicine, 天然產物研究與開發, 天然產物化學，等國內外多家刊物審稿人；
代表性學術論文🏌🏽♂️：
Wei Xiang, Li Xu , Li Zheng , Qi‑ao Zhang and Xiaowen Shi4*. Purifcation, structural characterization, and immunoregulatory activity of a polysaccharide from mulberry branch[J] Chemical and Biological Technologies in Agriculture,2024,11(39):748（二區）
Yurong Li, Long Guo, Juanjuan Wei, Yijun Yao, Li Xu *, Zhiqin Zhou*.Effect of polyethoxylated flavonoids (PMFs)-loaded citral and chitosan composite coatings on citrus preservation: From the perspective of fruit resistance[J] Food Chemistry: X, 2024,(22):101417（一區🛋，TOP）
Shanshan Liu , Xiaowen Shi, Wei Xiang*, Zhihui Jin, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, Xianzhi Huang, Li Xu*. Bioactivities and physicochemical properties of crude polysaccharides from mulberry twigs, agricultural by-products[J] Industrial Crops & Products, 2023, (193):116191（一區，TOP）
Xiaowen Shi , Li Xu*, Jianqin Zhang, Juanfen Mo , Pei Zhuang, Li Zheng*. Oxyresveratrol from mulberry branch extract protects HUVECs against oxidized Low-density Lipoprotein-induced oxidative injury via activation of the Nrf-2/HO-1 pathway[J] Journal of Functional Foods, 2022, (100):105371.（二區，TOP）
Pingkang Xu· Qimin Chen· Xiaoman Chen· Hao Qi· Yuyan Yang· Weiqi Li· Xin Yang· Amelia Gunawan· Shuoyu Chen· Huimin Zhang· Han‑Ming Shen· Dejian Huang Brian Kennedy Li Xu*·Ziyun Wu*. Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient‑sensing pathways[J] Gero Science, 2022,（45）：949-964（一區，TOP）
Fanshan Feng, Wei Xiang*, Han Gao, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, Xianzhi Huang, Li Xu*. Rapid Screening of Nonalkaloid α-Glucosidase Inhibitors from a Mulberry Twig Extract Using Enzyme-Functionalized Magnetic Nanoparticles Coupled with UPLC-MS/MS[J] Journal of Agricultural and Food Chemistry, 2022, (70):11958-11966（一區，TOP）
Yuyuan Zhu , Wei Xiang, Yao Shen, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Jiaxin Chen, You Zhou, Xin Xue, Xianzhi Huang, Li Xu*. New butyrylcholinesterase inhibitor derived from mulberry twigs, a kind of agricultural byproducts [J] Industrial Crops & Products, 2022, (187):11535（一區🚱，TOP）
Lin He, Feifei Huang, Yu Wang, Yijun Wu , Li Xu * and Pingan Chang. The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells[J] Metabolites, 2022, (12): 637.（二區）
Wei Xiang, Zhining Xia, Li Xu*. UPLC-MS/MS Profiling, Antioxidant, α-Glucosidase Inhibitory, Cholinesterase Inhibitory, and Cardiovascular Protection Potentials of Jialing 20 (Morus multicaulis Perr.) Mulberry Branch Extract [J] Foods, 2021, 10, 2659. （二區）
Jing Liu, Yan Yu, Yiping Zhao, Liangyu Jiang, You Zhou, Dejian Huang, Li Xu*. Interrelation of cholesterol-lowering, antioxidant activity and DNA damage protection to the different solvent extracts of mulberry (Morus alba L.) [J] Journal of food processing and preservation, 2020, 45(1): e14891
Ya-Nan Jia, Ya-Lin Peng, Yi-Ping Zhao, Xi-Fei Cheng, You Zhou, Chun-Li Chai, Ling-Shu Zeng, Min-Hui Pan, and Li Xu*Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs[J] Journal of Agricultural and Food Chemistry,2019, (67)5521-5529（一區🤨，TOP）
Ya-Nan Jia, Hai-Peng Lu, Ya-lin Peng, Bao-Shun Zhang, Xiao-bao Gong, Jun Su, You Zhou, Min-Hui Pan, Li Xu*. Oxyresveratrol prevents lipopolysaccharide/d galacto- samine induced acute liver injury in mice[J] International Immunopharmacology,2018, (56):105-112（二區，TOP）
Hai-Peng Lu, Ya-Nan Jia, Ya-Lin Peng, Yan Yu, Si-Long Sun, Meng-Ting Yue, Min-Hui Pan, Ling-Shu Zeng and Li Xu*. Oxyresveratrol, a Stilbene Compound from Morus alba L. Twig Extract Active Against Trichophyton rubrum[J] Phytotherapy Research, 2017, (31):1842-1848 （二區）
Hai Peng Lu, Ya Nan Jia, Yan Yu, and Li Xu*. DNA Protection Activity of a Hydroethanol Extract and Six Polyphenol Monomers from Morus alba L. (Mulberry) Twig [J] International Journal of Food Properties, 2017, 20(S2):S2207-S2219
Chao Liu, Wei Xiang, Yan Yu, Zhengqin Shi, Li Xu*. Comparative analysis of 1-deoxynojirimycin contribution degree to α-glucosidase inhibitory activity and physiological distribution in Morus alba L [J]. Industrial Crops and Products, 2015, 70: 309–315. （一區，TOP）
Li Xu*, Chao Liu, Wei Xiang, Chen Hu, Xiaoli Qin, Xianzhi Huang. Advances in the study of oxyresveratrol. International Journal of Pharmacology, 2014, 10(1): 44-54.
Chao Liu, Chuan-hong Wang, Jing Liu, Li Xu*. Optimization of microwave-assisted technology for extracting 1-deoxynojirimycin from mulberry tea by response surface methodology [J]. Food Science and Technology Research, 2014, 20(3): 599-603.
Li Xu*, Jing Liu, Chao Liu, Chun Wu, Chuan-Hong Wang, Xian-Zhi Huang. Response surface optimization of ultrasonic-assisted oxyres- veratrol extraction from the bark of cultured black mulberry (Morus nigra L.) [J]. Separation Science and Technology, 2013, 48: 2779–2785.
出版學術專著：
參編《中國農作物病蟲害》（第三版），中國農業出版社🛸，2015
聯系方式：
地 址：400716，西南大學蠶桑紡織與生物質科學天辰應用生物技術研究室 |
